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Protective Efficacy of the OprF/OprI/PcrV Recombinant Chimeric Protein Against Pseudomonas aeruginosa in the Burned BALB/c Mouse Model

BACKGROUND: Pseudomonas aeruginosa infection is the major cause of death in burn patients. Thus, in this study, a chimeric vaccine harboring the OprF(185–350)–OprI(22–83)–PcrV was designed and expressed in Escherichia coli. The immunogenicity of the recombinant chimer, OprI, OprF, and PcrV was studi...

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Detalhes bibliográficos
Publicado no:Infect Drug Resist
Main Authors: Fakoor, Mohammad Hadi, Mousavi Gargari, Seyed Latif, Owlia, Parviz, Sabokbar, Azar
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7294051/
https://ncbi.nlm.nih.gov/pubmed/32606816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S244081
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