Enhanced Immunogenicity in the Murine Airway Mucosa with an Attenuated Salmonella Live Vaccine Expressing OprF-OprI from Pseudomonas aeruginosa

We constructed an oral live vaccine based on the attenuated aroA mutant Salmonella enterica serovar Typhimurium strain SL3261 expressing outer membrane proteins F and I (OprF-OprI) from Pseudomonas aeruginosa and investigated it in a mouse model. Strains with in vivo inducible protein expression wit...

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Detalhes bibliográficos
Main Authors: Arnold, Heinz, Bumann, Dirk, Felies, Melanie, Gewecke, Britta, Sörensen, Meike, Gessner, J. Engelbert, Freihorst, Joachim, von Specht, Bernd Ulrich, Baumann, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC523058/
https://ncbi.nlm.nih.gov/pubmed/15501786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.11.6546-6553.2004
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