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Spacer-mediated Control of Coumarin Uncaging for Photocaged Thymidine

Despite its importance in the design of photocaged molecules, less attention is focused on linker chemistry than the cage itself. Here, we describe unique uncaging properties displayed by two coumarin-caged thymidine compounds, each conjugated with (2) or without (1) an extended, self-immolative spa...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Tang, Shengzhuang, Cannon, Jayme, Yang, Kelly, Krummel, Matthew F., Baker, James R., Choi, Seok Ki
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293860/
https://ncbi.nlm.nih.gov/pubmed/32020803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02617
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