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Robust combination of liver stereotactic body radiotherapy modulates pharmacokinetics of sorafenib toward preferable parameters

To evaluate the effect and mechanism of radiotherapy (RT)–sorafenib pharmacokinetics (PK) in different regimens with conventional or high dose irradiation. Between February 2012 and December 2018, 43 patients with portal vein tumor thrombosis treated with sorafenib plus conventional RT (58%) or ster...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hsieh, Chen-Hsi, Chen, Yu-Jen, Tsai, Tung-Hu, Wang, Li-Ying, Tai, Hung-Chi, Huang, Hsiang-Ling, Huang, Yu-Chuen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293270/
https://ncbi.nlm.nih.gov/pubmed/32533042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66583-9
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