Adipocyte G(i) signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity

Adipocyte dysfunction links obesity to insulin resistance and type 2 diabetes. Adipocyte function is regulated by receptor-mediated activation of heterotrimeric G proteins. Little is known about the potential in vivo metabolic roles of G(i)-type G proteins expressed by adipocytes, primarily due to t...

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Опубликовано в: :Nat Commun
Главные авторы: Wang, Lei, Pydi, Sai P., Zhu, Lu, Barella, Luiz F., Cui, Yinghong, Gavrilova, Oksana, Bence, Kendra K., Vernochet, Cecile, Wess, Jürgen
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293267/
https://ncbi.nlm.nih.gov/pubmed/32532984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16756-x
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