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TECPR1 promotes aggrephagy by direct recruitment of LC3C autophagosomes to lysosomes
The accumulation of protein aggregates is involved in the onset of many neurodegenerative diseases. Aggrephagy is a selective type of autophagy that counteracts neurodegeneration by degrading such aggregates. In this study, we found that LC3C cooperates with lysosomal TECPR1 to promote the degradati...
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| Yayımlandı: | Nat Commun |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group UK
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7293217/ https://ncbi.nlm.nih.gov/pubmed/32532970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16689-5 |
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