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Structural disruption of exonic stem–loops immediately upstream of the intron regulates mammalian splicing

Recognition of highly degenerate mammalian splice sites by the core spliceosomal machinery is regulated by several protein factors that predominantly bind exonic splicing motifs. These are postulated to be single-stranded in order to be functional, yet knowledge of secondary structural features that...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Saha, Kaushik, England, Whitney, Fernandez, Mike Minh, Biswas, Tapan, Spitale, Robert C, Ghosh, Gourisankar
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293017/
https://ncbi.nlm.nih.gov/pubmed/32402057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa358
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