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Structural disruption of exonic stem–loops immediately upstream of the intron regulates mammalian splicing

Recognition of highly degenerate mammalian splice sites by the core spliceosomal machinery is regulated by several protein factors that predominantly bind exonic splicing motifs. These are postulated to be single-stranded in order to be functional, yet knowledge of secondary structural features that...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Saha, Kaushik, England, Whitney, Fernandez, Mike Minh, Biswas, Tapan, Spitale, Robert C, Ghosh, Gourisankar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293017/
https://ncbi.nlm.nih.gov/pubmed/32402057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa358
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