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Integrating NMR and simulations reveals motions in the UUCG tetraloop

We provide an atomic-level description of the structure and dynamics of the UUCG RNA stem–loop by combining molecular dynamics simulations with experimental data. The integration of simulations with exact nuclear Overhauser enhancements data allowed us to characterize two distinct states of this mol...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Bottaro, Sandro, Nichols, Parker J, Vögeli, Beat, Parrinello, Michele, Lindorff-Larsen, Kresten
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7293013/
https://ncbi.nlm.nih.gov/pubmed/32427326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa399
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