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GGTA1/iGb3S Double Knockout Mice: Immunological Properties and Immunogenicity Response to Xenogeneic Bone Matrix

BACKGROUND: Animal tissues and tissue-derived biomaterials are widely used in the field of xenotransplantation and regenerative medicine. A potential immunogenic risk that affects the safety and effectiveness of xenografts is the presence of remnant α-Gal antigen (synthesized by GGTA1 or/and iGb3S)....

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Shao, Anliang, Ling, You, Chen, Liang, Wei, Lina, Fan, Changfa, Lei, Dan, Xu, Liming, Wang, Chengbin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292995/
https://ncbi.nlm.nih.gov/pubmed/32596401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/9680474
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