Unbound Plasma, Total Plasma, and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation

ABSTRACT: Therapeutic drug monitoring of tacrolimus whole-blood concentrations is standard care in thoracic organ transplantation. Nevertheless, toxicity may appear with alleged therapeutic concentrations possibly related to variability in unbound concentrations. However, pharmacokinetic data on unb...

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Dettagli Bibliografici
Pubblicato in:Clin Pharmacokinet
Autori principali: Sikma, Maaike A., Van Maarseveen, Erik M., Hunault, Claudine C., Moreno, Javier M., Van de Graaf, Ed A., Kirkels, Johannes H., Verhaar, Marianne C., Grutters, Jan C., Kesecioglu, Jozef, De Lange, Dylan W., Huitema, Alwin D. R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2019
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Original Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7292814/
https://ncbi.nlm.nih.gov/pubmed/31840222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00854-1
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