Ras activation contributes to the maintenance and expansion of Sca-1(pos) cells in a mouse model of breast cancer

The cancer stem cell (CSC) hypothesis proposes that CSCs are the root of cancer and cause cancer metastasis and recurrence. In this study, we examined whether Ras signaling is associated with stemness of the CSCs population characterized by the stem cell antigen (Sca-1) phenotype in a 4T1 syngeneic...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Kim, Ran-Ju, Kim, Soo-Rim, Roh, Kyung-Jin, Park, Sang-Bum, Park, Jeong-Ran, Kang, Kyung-Sun, Kong, Gu, Tang, Binwu, Yang, Yu-an, Kohn, Ethan A., Wakefield, Lalage M., Nam, Jeong-Seok
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291698/
https://ncbi.nlm.nih.gov/pubmed/19586713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2009.06.010
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