NELL-1 induces Sca-1(+) mesenchymal progenitor cell expansion in models of bone maintenance and repair

NELL-1 is a secreted, osteogenic protein first discovered to control ossification of the cranial skeleton. Recently, NELL-1 has been implicated in bone maintenance. However, the cellular determinants of NELL-1’s bone-forming effects are still unknown. Here, recombinant human NELL-1 (rhNELL-1) implan...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: James, Aaron W., Shen, Jia, Tsuei, Rebecca, Nguyen, Alan, Khadarian, Kevork, Meyers, Carolyn A., Pan, Hsin Chuan, Li, Weiming, Kwak, Jin H., Asatrian, Greg, Culiat, Cymbeline T., Lee, Min, Ting, Kang, Zhang, Xinli, Soo, Chia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470886/
https://ncbi.nlm.nih.gov/pubmed/28614787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92573
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