NELL-1 induces Sca-1(+) mesenchymal progenitor cell expansion in models of bone maintenance and repair

NELL-1 is a secreted, osteogenic protein first discovered to control ossification of the cranial skeleton. Recently, NELL-1 has been implicated in bone maintenance. However, the cellular determinants of NELL-1’s bone-forming effects are still unknown. Here, recombinant human NELL-1 (rhNELL-1) implan...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: James, Aaron W., Shen, Jia, Tsuei, Rebecca, Nguyen, Alan, Khadarian, Kevork, Meyers, Carolyn A., Pan, Hsin Chuan, Li, Weiming, Kwak, Jin H., Asatrian, Greg, Culiat, Cymbeline T., Lee, Min, Ting, Kang, Zhang, Xinli, Soo, Chia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470886/
https://ncbi.nlm.nih.gov/pubmed/28614787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92573
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