A phase 1 trial of the safety, tolerability and biological effects of intravenous Enadenotucirev, a novel oncolytic virus, in combination with chemoradiotherapy in locally advanced rectal cancer (CEDAR)

BACKGROUND: Chemoradiotherapy remains the standard of care for locally advanced rectal cancer. Efforts to intensify treatment and increase response rates have yet to yield practice changing results due to increased toxicity and/or absence of increased radiosensitization. Enadenotucirev (EnAd) is a t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Radiat Oncol
Päätekijät: O’Cathail, Séan M., Davis, Steven, Holmes, Jane, Brown, Richard, Fisher, Kerry, Seymour, Leonard, Adams, Richard, Good, James, Sebag-Montefiore, David, Maughan, Tim, Hawkins, Maria A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2020
Aiheet:
Study Protocol
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291514/
https://ncbi.nlm.nih.gov/pubmed/32532291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-020-01593-5
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