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SURF: integrative analysis of a compendium of RNA-seq and CLIP-seq datasets highlights complex governing of alternative transcriptional regulation by RNA-binding proteins

Advances in high-throughput profiling of RNA-binding proteins (RBPs) have resulted inCLIP-seq datasets coupled with transcriptome profiling by RNA-seq. However, analysis methods that integrate both types of data are lacking. We describe SURF, Statistical Utility for RBP Functions, for integrative an...

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Publicat a:Genome Biol
Autors principals: Chen, Fan, Keleş, Sündüz
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291511/
https://ncbi.nlm.nih.gov/pubmed/32532357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02039-7
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