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Identification of hub genes associated with RNAi-induced silencing of XIAP through targeted proteomics approach in MCF7 cells

BACKGROUND: The X-linked inhibitor of apoptosis protein (XIAP) is the most potent caspase inhibitor of the IAP family in apoptosis pathway. This study aims to identify the molecular targets of XIAP in human breast cancer cells exposed to XIAP siRNA by proteomics screening. The expression of XIAP was...

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Publié dans:Cell Biosci
Auteurs principaux: Gholizadeh, Mehdi Agha, Shamsabadi, Fatemeh T., Yamchi, Ahad, Golalipour, Masoud, Jhingan, Gagan Deep, Shahbazi, Majid
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291505/
https://ncbi.nlm.nih.gov/pubmed/32537125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00437-9
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