Safety and efficacy of glibenclamide combined with rtPA in acute cerebral ischemia with occlusion/stenosis of anterior circulation (SE-GRACE): study protocol for a randomized controlled trial

BACKGROUND: Thrombolysis with recombinant tissue plasminogen activator (rtPA) improves outcome for patients with acute ischemic stroke (AIS), but many of them still have substantial disability. Glibenclamide (US adopted name, glyburide), a long-acting sulfonylurea, shows promising result in treating...

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Publicado en:BMC Neurol
Autores principales: Huang, Kaibin, Ji, Zhong, Wu, Yongming, Huang, Yunqiang, Li, Guangning, Zhou, Saijun, Yang, Zhi, Huang, Wenguo, Yang, Guoshuai, Weng, Guohu, Chen, Pingyan, Pan, Suyue
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
Materias:
Study Protocol
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291425/
https://ncbi.nlm.nih.gov/pubmed/32527232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-020-01823-z
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