Isoprenylcysteine Carboxyl Methyltransferase and Its Substrate Ras Are Critical Players Regulating TLR-Mediated Inflammatory Responses

In this study, we investigated the functional role of isoprenylcysteine carboxyl methyltransferase (ICMT) and its methylatable substrate Ras in Toll-like receptor (TLR)-activated macrophages and in mouse inflammatory disease conditions. ICMT and RAS expressions were strongly increased in macrophages...

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Bibliografske podrobnosti
izdano v:Cells
Main Authors: Yang, Woo Seok, Kim, Han Gyung, Kim, Eunji, Han, Sang Yun, Aziz, Nur, Yi, Young-Su, Kim, Sunggyu, Lee, Yunmi, Yoo, Byong Chul, Han, Jeung-Whan, Parameswaran, Narayanan, Kim, Ji Hye, Cho, Jae Youl
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291029/
https://ncbi.nlm.nih.gov/pubmed/32422978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9051216
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