Current Challenges in Providing Good Leukapheresis Products for Manufacturing of CAR-T Cells for Patients with Relapsed/Refractory NHL or ALL

Background: T lymphocyte collection through leukapheresis is an essential step for chimeric antigen receptor T (CAR-T) cell therapy. Timing of apheresis is challenging in heavily pretreated patients who suffer from rapid progressive disease and receive T cell impairing medication. Methods: A total o...

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Publicado no:Cells
Main Authors: Korell, Felix, Laier, Sascha, Sauer, Sandra, Veelken, Kaya, Hennemann, Hannah, Schubert, Maria-Luisa, Sauer, Tim, Pavel, Petra, Mueller-Tidow, Carsten, Dreger, Peter, Schmitt, Michael, Schmitt, Anita
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290830/
https://ncbi.nlm.nih.gov/pubmed/32429189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9051225
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