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Application of CRISPR Tools for Variant Interpretation and Disease Modeling in Inherited Retinal Dystrophies

Inherited retinal dystrophies are an assorted group of rare diseases that collectively account for the major cause of visual impairment of genetic origin worldwide. Besides clinically, these vision loss disorders present a high genetic and allelic heterogeneity. To date, over 250 genes have been ass...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Fuster-García, Carla, García-Bohórquez, Belén, Rodríguez-Muñoz, Ana, Millán, José M., García-García, Gema
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290804/
https://ncbi.nlm.nih.gov/pubmed/32349249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11050473
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