Repurposing Cancer Drugs Batimastat and Marimastat to Inhibit the Activity of a Group I Metalloprotease from the Venom of the Western Diamondback Rattlesnake, Crotalus atrox

Snakebite envenomation causes over 140,000 deaths every year, predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases. It is associated with incredibly complex pathophysiology due to the vast number of unique toxins/proteins present in the venoms...

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Dettagli Bibliografici
Pubblicato in:Toxins (Basel)
Autori principali: Layfield, Harry J., Williams, Harry F., Ravishankar, Divyashree, Mehmi, Amita, Sonavane, Medha, Salim, Anika, Vaiyapuri, Rajendran, Lakshminarayanan, Karthik, Vallance, Thomas M., Bicknell, Andrew B., Trim, Steven A., Patel, Ketan, Vaiyapuri, Sakthivel
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290494/
https://ncbi.nlm.nih.gov/pubmed/32397419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12050309
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