Repurposing Cancer Drugs Batimastat and Marimastat to Inhibit the Activity of a Group I Metalloprotease from the Venom of the Western Diamondback Rattlesnake, Crotalus atrox

Snakebite envenomation causes over 140,000 deaths every year, predominantly in developing countries. As a result, it is one of the most lethal neglected tropical diseases. It is associated with incredibly complex pathophysiology due to the vast number of unique toxins/proteins present in the venoms...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Layfield, Harry J., Williams, Harry F., Ravishankar, Divyashree, Mehmi, Amita, Sonavane, Medha, Salim, Anika, Vaiyapuri, Rajendran, Lakshminarayanan, Karthik, Vallance, Thomas M., Bicknell, Andrew B., Trim, Steven A., Patel, Ketan, Vaiyapuri, Sakthivel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290494/
https://ncbi.nlm.nih.gov/pubmed/32397419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12050309
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