Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms

Much of what is known about the neurotrophic receptor tyrosine kinase (NTRK) genes in cancer was revealed through identification and characterization of activating Trk fusions across many tumor types. A resurgence of interest in these receptors has emerged owing to the realization that they are prom...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Joshi, Sunil K., Qian, Kristin, Bisson, William H., Watanabe-Smith, Kevin, Huang, Ariane, Bottomly, Daniel, Traer, Elie, Tyner, Jeffrey W., McWeeney, Shannon K., Davare, Monika A., Druker, Brian J., Tognon, Cristina E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2020
Fag:
Myeloid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290093/
https://ncbi.nlm.nih.gov/pubmed/32315394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003691
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