Topical application of endothelin receptor a antagonist attenuates imiquimod-induced psoriasiform skin inflammation

Endothelin-1 (ET-1) is well known as the most potent vasoconstrictor, and can evoke histamine-independent pruritus. Recently, its involvement in cutaneous inflammation has begun to draw attention. The upregulation of ET-1 expression in the epidermis of human psoriasis patients has been reported. It...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Nakahara, Takeshi, Kido-Nakahara, Makiko, Ulzii, Dugarmaa, Miake, Sho, Fujishima, Kei, Sakai, Sawako, Chiba, Takahito, Tsuji, Gaku, Furue, Masutaka
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289852/
https://ncbi.nlm.nih.gov/pubmed/32528072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66490-z
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