Scratching Counteracts IL-13 Signaling by Upregulating the Decoy Receptor IL-13Rα2 in Keratinocytes

The vicious itch–scratch cycle is a cardinal feature of atopic dermatitis (AD), in which IL-13 signaling plays a dominant role. Keratinocytes express two receptors: The heterodimeric IL-4Rα/IL-13Rα1 and IL-13Rα2. The former one transduces a functional IL-13 signal, whereas the latter IL-13Rα2 works...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Ulzii, Dugarmaa, Kido-Nakahara, Makiko, Nakahara, Takeshi, Tsuji, Gaku, Furue, Kazuhisa, Hashimoto-Hachiya, Akiko, Furue, Masutaka
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651282/
https://ncbi.nlm.nih.gov/pubmed/31284553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133324
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