Spatial Compartmentalization of the Microbiome between the Lumen and Crypts Is Lost in the Murine Cecum following the Process of Surgery, Including Overnight Fasting and Exposure to Antibiotics

The cecum is a unique region in the mammalian intestinal tract in which the microbiome is localized to two compartments, the lumen and the crypts. The microbiome within crypts is particularly important as it is in direct contact with lining epithelial cells including stem cells. Here, we analyzed th...

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Vydáno v:mSystems
Hlavní autoři: Zaborin, Alexander, Penalver Bernabe, Beatriz, Keskey, Robert, Sangwan, Naseer, Hyoju, Sanjiv, Gottel, Neil, Gilbert, Jack A., Zaborina, Olga, Alverdy, John C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289591/
https://ncbi.nlm.nih.gov/pubmed/32518197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00377-20
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