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Bromodomain AAA+ ATPases get into shape

Bromodomain AAA+ ATPases (ATPases associated with diverse cellular activities) are emerging as oncogenic proteins and compelling targets for anticancer therapies. However, structural and biochemical insight into these machines is missing. A recent study by Cho et al. reports the first cryo-EM struct...

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Detalhes bibliográficos
Publicado no:Nucleus
Main Authors: Murawska, Magdalena, Ladurner, Andreas G.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7289582/
https://ncbi.nlm.nih.gov/pubmed/32191554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2020.1741304
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