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A Twist between ROS and Sperm-Mediated Intergenerational Epigenetic Inheritance
Yoshida et al. (2020) report in this issue of Molecular Cell that a paternal low-protein diet elevates ROS in the testicular germ cells, altering ATF7 activity and H3K9me2 abundance on target genes, including tRNA loci. These changes are maintained in spermatozoa, regulating tsRNA biogenesis, and to...
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| 出版年: | Mol Cell |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7289451/ https://ncbi.nlm.nih.gov/pubmed/32386538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.04.003 |
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