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Intergenerational epigenetic inheritance of cancer susceptibility in mammals

Susceptibility to cancer is heritable, but much of this heritability remains unexplained. Some ‘missing’ heritability may be mediated by epigenetic changes in the parental germ line that do not involve transmission of genetic variants from parent to offspring. We report that deletion of the chromati...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Lesch, Bluma J, Tothova, Zuzana, Morgan, Elizabeth A, Liao, Zhicong, Bronson, Roderick T, Ebert, Benjamin L, Page, David C
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456297/
https://ncbi.nlm.nih.gov/pubmed/30963999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39380
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