Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson’s Disease

We report the implantation of patient-derived midbrain dopaminergic progenitor cells, differentiated in vitro from autologous induced pluripotent stem cells (iPSCs), in a patient with idiopathic Parkinson’s disease. The patient-specific progenitor cells were produced under Good Manufacturing Practic...

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Published in:N Engl J Med
Main Authors: Schweitzer, Jeffrey S., Song, Bin, Herrington, Todd M., Park, Tae-Yoon, Lee, Nayeon, Ko, Sanghyeok, Jeon, Jeha, Cha, Young, Kim, Kyungsang, Li, Quanzheng, Henchcliffe, Claire, Kaplitt, Michael, Neff, Carolyn, Rapalino, Otto, Seo, Hyemyung, Lee, In-Hee, Kim, Jisun, Kim, Taewoo, Petsko, Gregory A., Ritz, Jerome, Cohen, Bruce M., Kong, Sek-Won, Leblanc, Pierre, Carter, Bob S., Kim, Kwang-Soo
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288982/
https://ncbi.nlm.nih.gov/pubmed/32402162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1915872
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