RUNX1-205, a novel splice variant of the human RUNX1 gene, has blockage effect on mesoderm–hemogenesis transition and promotion effect during the late stage of hematopoiesis

Runt-related transcription factor 1 (RUNX1) is required for definitive hematopoiesis; however, the functions of most human RUNX1 isoforms are unclear. In particular, the effects of RUNX1-205 (a novel splice variant that lacks exon 6 in comparison with RUNX1b) on human hematopoiesis are not clear. In...

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Udgivet i:J Mol Cell Biol
Main Authors: Sun, Wencui, Zeng, Jiahui, Chang, Jing, Xue, Yuan, Zhang, Yonggang, Pan, Xu, Zhou, Ya, Lai, Mowen, Bian, Guohui, Zhou, Qiongxiu, Liu, Jiaxing, Chen, Bo, Ma, Feng
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288743/
https://ncbi.nlm.nih.gov/pubmed/32313936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjaa019
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