The Predicted Indirectly Recognizable HLA Epitopes (PIRCHE) Score for HLA Class I Graft-Versus-Host Disparity Is Associated with Increased Acute Graft-Versus-Host Disease in Haploidentical Transplantation with Post-Transplant Cyclophosphamide

The Predicted Indirectly Recognizable HLA Epitopes (PIRCHE) score quantifies the number of PIRCHE between patient and donor pairs and represents an in silico measure of indirect alloreactivity. This biologic process is defined as T cell recognition of epitopes derived from mismatched, allogeneic HLA...

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Bibliographische Detailangaben
Veröffentlicht in:Biol Blood Marrow Transplant
Hauptverfasser: Rimando, Joseph, Slade, Michael, DiPersio, John F., Westervelt, Peter, Gao, Feng, Liu, Chang, Romee, Rizwan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286229/
https://ncbi.nlm.nih.gov/pubmed/31563575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2019.09.024
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