The Predicted Indirectly Recognizable HLA Epitopes (PIRCHE) Score for HLA Class I Graft-Versus-Host Disparity Is Associated with Increased Acute Graft-Versus-Host Disease in Haploidentical Transplantation with Post-Transplant Cyclophosphamide

The Predicted Indirectly Recognizable HLA Epitopes (PIRCHE) score quantifies the number of PIRCHE between patient and donor pairs and represents an in silico measure of indirect alloreactivity. This biologic process is defined as T cell recognition of epitopes derived from mismatched, allogeneic HLA...

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Publicado en:Biol Blood Marrow Transplant
Main Authors: Rimando, Joseph, Slade, Michael, DiPersio, John F., Westervelt, Peter, Gao, Feng, Liu, Chang, Romee, Rizwan
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286229/
https://ncbi.nlm.nih.gov/pubmed/31563575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2019.09.024
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