Tideglusib, a prospective alternative to nonoxynol-9 contraceptive

OBJECTIVES: We aimed to evaluate the antifertility activity and vaginal irritation effects of tideglusib in vivo using rabbit models and to evaluate the cytotoxical effects of tideglusib to sperm, vaginal cells and vaginal bacteria (L. acidophilus) in vitro. STUDY DESIGN: We treated female rabbits w...

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Dettagli Bibliografici
Pubblicato in:Contracept X
Autori principali: Chen, Zhiting, Shu, Niyan, Wang, Yuzhu, Yang, Yiting, Shao, Zhiyu, Tian, Fang, Xia, Minjie, Wang, Zhikai, Wang, Xin, Feng, Xing, Huang, Xianliang, Li, Weihua, Yu, Heguo, Diao, Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286178/
https://ncbi.nlm.nih.gov/pubmed/32550526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conx.2019.100007
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