Tideglusib, a prospective alternative to nonoxynol-9 contraceptive

OBJECTIVES: We aimed to evaluate the antifertility activity and vaginal irritation effects of tideglusib in vivo using rabbit models and to evaluate the cytotoxical effects of tideglusib to sperm, vaginal cells and vaginal bacteria (L. acidophilus) in vitro. STUDY DESIGN: We treated female rabbits w...

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Detalhes bibliográficos
Publicado no:Contracept X
Main Authors: Chen, Zhiting, Shu, Niyan, Wang, Yuzhu, Yang, Yiting, Shao, Zhiyu, Tian, Fang, Xia, Minjie, Wang, Zhikai, Wang, Xin, Feng, Xing, Huang, Xianliang, Li, Weihua, Yu, Heguo, Diao, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286178/
https://ncbi.nlm.nih.gov/pubmed/32550526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conx.2019.100007
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