The use of the dynamic weight bearing test to assess the effects of acute, intramuscularly administered botulinum neurotoxin type A1 in rats

Assessing the efficacy of botulinum neurotoxin (BoNT) in vivo is essential given the growing number of BoNT products used in the clinic. Here, we evaluated the dynamic weight bearing (DWB) test for sensitivity to paralytic effects of BoNT-A following intramuscular administration. The toxin was admin...

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Vydáno v:Toxicon X
Hlavní autoři: Cornet, Sylvie, Périer, Cindy, Wagner, Stéphanie, Andriambeloson, Emile, Pouzet, Bruno, Kalinichev, Mikhail
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286111/
https://ncbi.nlm.nih.gov/pubmed/32550595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxcx.2020.100041
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