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Creation and testing of a new, local microtubule-disruption tool based on the microtubule-severing enzyme, katanin p60
Current methods to disrupt the microtubule cytoskeleton do not easily provide rapid, local control with standard cell manipulation reagents. Here, we develop a new microtubule-disruption tool based on katanin p60 severing activity and demonstrate proof-of-principle by targeting it to kinetochores in...
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| Publicado no: | Cytoskeleton (Hoboken) |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7286084/ https://ncbi.nlm.nih.gov/pubmed/30176123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21482 |
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