Frequency of radiation-induced malignancies post–adjuvant radiotherapy for breast cancer in patients with Li-Fraumeni syndrome

PURPOSE: Women with Li-Fraumeni syndrome (LFS), a cancer predisposition syndrome caused by germline mutations in TP53, have an over 50% risk of developing breast cancer by age 70. Patients with LFS are at risk for radiation-induced malignancies; however, only small case series have prior investigate...

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Publié dans:Breast Cancer Res Treat
Auteurs principaux: Le, Anh N., Harton, Joanna, Desai, Heena, Powers, Jacquelyn, Zelley, Kristin, Bradbury, Angela, Nathanson, Katherine, Shah, Payal D., Doucette, Abigail, Freedman, Gary, Gabriel, Peter, Domchek, Susan M., MacFarland, Suzanne P., Maxwell, Kara N.
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7285877/
https://ncbi.nlm.nih.gov/pubmed/32246378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-020-05612-7
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