Frequency of radiation-induced malignancies post–adjuvant radiotherapy for breast cancer in patients with Li-Fraumeni syndrome

PURPOSE: Women with Li-Fraumeni syndrome (LFS), a cancer predisposition syndrome caused by germline mutations in TP53, have an over 50% risk of developing breast cancer by age 70. Patients with LFS are at risk for radiation-induced malignancies; however, only small case series have prior investigate...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Le, Anh N., Harton, Joanna, Desai, Heena, Powers, Jacquelyn, Zelley, Kristin, Bradbury, Angela, Nathanson, Katherine, Shah, Payal D., Doucette, Abigail, Freedman, Gary, Gabriel, Peter, Domchek, Susan M., MacFarland, Suzanne P., Maxwell, Kara N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7285877/
https://ncbi.nlm.nih.gov/pubmed/32246378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-020-05612-7
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