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Contributions of Dickkopf‐1 to Obesity‐Induced Bone Loss and Marrow Adiposity

Low bone strength in overweight individuals is a significant medical problem. One important determinant of mesenchymal stem cell fate into osteoblasts or adipocytes is the Wnt signaling pathway. We recently showed that Dickkopf‐1 (DKK1), a potent Wnt inhibitor, is upregulated in obese mice. In this...

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Bibliographic Details
Published in:JBMR Plus
Main Authors: Colditz, Juliane, Picke, Ann‐Kristin, Hofbauer, Lorenz C., Rauner, Martina
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Inc. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7285751/
https://ncbi.nlm.nih.gov/pubmed/32537550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm4.10364
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