Ethyl pyruvate protects against sepsis-associated encephalopathy through inhibiting the NLRP3 inflammasome

BACKGROUND: With the advance of antibiotics and life support therapy, the mortality of sepsis has been decreasing in recent years. However, the incidence of sepsis-associated encephalopathy (SAE), a common complication of sepsis, is still high. There are few effective therapies to treat clinical SAE...

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Publicat a:Mol Med
Autors principals: Zhong, Xiaoli, Xie, Lingli, Yang, Xiaolong, Liang, Fang, Yang, Yanliang, Tong, Jianbin, Zhong, Yanjun, Zhao, Kai, Tang, Yiting, Yuan, Chuang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7285451/
https://ncbi.nlm.nih.gov/pubmed/32517686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-020-00181-3
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