Autoimmune Mechanisms of Interferon Hypersensitivity and Neurodegenerative Diseases: Down Syndrome

Down syndrome (DS), also known as trisomy 21 (T21), is associated with interferon (IFN) hypersensitivity, as well as predilections for Alzheimer's dementia (AD) and various autoimmune diseases. IFN-α and IFN-γ receptors are encoded on chromosome 21 (Ch21). It remains unclear how other Ch21 gene...

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Bibliographic Details
Published in:Autoimmune Dis
Main Authors: Jagadeesh, Ashraya, Maroun, Leonard E., Van Es, Lisa M., Millis, Richard M.
Format: Artigo
Language:Inglês
Published: Hindawi 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7285398/
https://ncbi.nlm.nih.gov/pubmed/32566271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6876920
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