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The Correlation between Physical Crosslinking and Water-Soluble Drug Release from Chitosan-Based Microparticles
Microparticles containing water-soluble zidovudine were prepared by spray-drying using chitosan glutamate and beta-glycerophosphate as an ion crosslinker (CF). The Box–Behnken design was applied to optimize the microparticles in terms of their drug loading and release behavior. Physicochemical studi...
Tallennettuna:
| Julkaisussa: | Pharmaceutics |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
MDPI
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7284795/ https://ncbi.nlm.nih.gov/pubmed/32429349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12050455 |
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