Donor bone-marrow CXCR4+ Foxp3+ T-regulatory cells are essential for costimulation blockade-induced long-term survival of murine limb transplants

Vascularized composite allotransplantation (VCA) allows tissue replacement after devastating loss but is currently limited in application and may be more widely performed if maintenance immunosuppression was not essential for graft acceptance. We tested whether peri-transplant costimulation blockade...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Wang, Liqing, Wang, Zhonglin, Han, Rongxiang, Samanta, Arabinda, Ge, Guanghui, Levin, L. Scott, Levine, Matthew H., Hancock, Wayne W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7283338/
https://ncbi.nlm.nih.gov/pubmed/32518311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66139-x
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