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Cardio-renal protective effect of the xanthine oxidase inhibitor febuxostat in the 5/6 nephrectomy model with hyperuricemia

Although hyperuricemia has been shown to be associated with the progression of cardiovascular disorder and chronic kidney disease (CKD), there is conflicting evidence as to whether xanthine oxidase (XO) inhibitors confer organ protection besides lowering serum urate levels. In this study, we address...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Omizo, Hiroki, Tamura, Yoshifuru, Morimoto, Chikayuki, Ueno, Masaki, Hayama, Yuto, Kuribayashi-Okuma, Emiko, Uchida, Shunya, Shibata, Shigeru
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7283314/
https://ncbi.nlm.nih.gov/pubmed/32518351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65706-6
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