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Zoledronic acid inhibits the growth of leukemic MLL-AF9 transformed hematopoietic cells
A leukemic in vitro model produced by transducing Cord Blood derived-hematopoietic CD34(+) cells with the MLL-AF9 translocation resulting in the oncogenic fusion protein, is used to assess for sensitivity to Zoledronic acid. These cells are practically immortalized and are of myeloid origin. Prolife...
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Publicado no: | Heliyon |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2020
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7283156/ https://ncbi.nlm.nih.gov/pubmed/32529062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e04020 |
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