The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway

ZNF521 is a transcription co-factor with recognized regulatory functions in haematopoietic, osteo-adipogenic and neural progenitor cells. Among its diverse activities, ZNF521 has been implicated in the regulation of medulloblastoma (MB) cells, where the Hedgehog (HH) pathway, has a key role in the d...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Scicchitano, Stefania, Giordano, Marco, Lucchino, Valeria, Montalcini, Ylenia, Chiarella, Emanuela, Aloisio, Annamaria, Codispoti, Bruna, Zoppoli, Pietro, Melocchi, Valentina, Bianchi, Fabrizio, De Smaele, Enrico, Mesuraca, Maria, Morrone, Giovanni, Bond, Heather M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6763495/
https://ncbi.nlm.nih.gov/pubmed/31558698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1946-x
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