The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription

Dysregulation of CDK8 (Cyclin-Dependent Kinase 8) and its regulatory partner CycC (Cyclin C), two subunits of the conserved Mediator (MED) complex, have been linked to diverse human diseases such as cancer. Thus, it is essential to understand the regulatory network modulating the CDK8-CycC complex i...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Li, Xiao, Liu, Mengmeng, Ren, Xingjie, Loncle, Nicolas, Wang, Qun, Hemba-Waduge, Rajitha-Udakara-Sampath, Yu, Stephen H., Boube, Muriel, Bourbon, Henri-Marc G., Ni, Jian-Quan, Ji, Jun-Yuan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7282676/
https://ncbi.nlm.nih.gov/pubmed/32463833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008832
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