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R269C variant of ESR1: high prevalence and differential function in a subset of pancreatic cancers
BACKGROUND: Estrogen receptor α (ESR1) plays a critical role in promoting growth of various cancers. Yet, its role in the development of pancreatic cancer is not well-defined. A less studied region of ESR1 is the hinge region, connecting the ligand binding and DNA domains. rs142712646 is a rare SNP...
Zapisane w:
| Wydane w: | BMC Cancer |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7282172/ https://ncbi.nlm.nih.gov/pubmed/32513126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07005-x |
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